Testosterone Propionate inj. 100mg/ml is a basic anabolic steroid (synthetic substance related to male sex hormones) commonly used by body-builders and athletes for the enhancement of their physique and performance. It acts like the body’s natural testosterone, which is responsible for the growth and development of the body muscles.
What are the uses of testosterone propionate inj.100 mg/ml?
- Testosterone propionate inj. is primarily used by men for various functions such as growth and development of the muscles, bones, and genitals. It also helps burn fat, increases libido, and reduces the risk of heart diseases.
- The drug is recommended to treat several health conditions like reduced activity of testis, primary testicular failure due to inflammation of testis, undescended testicle or absence of testicles, Klinefelter syndrome, and suboptimal functioning of testes or ovaries caused by chemotherapy.
- The drug is prescribed for women to treat neurological disorders, dysfunctional uterine bleeding (in older women) and ovarian cancer.
- The drug used to treat significant weight loss in HIV and unusual delayed sexual maturity.
- The drug is popular among athletes and body builders as it shows quick action and is excreted out of the body within two to three days.
How does testosterone propionate inj.100 mg/ml act?
Testosterone propionate is the shortest ester, which means it leaves the parent hormone (testosterone) in the least amount of time. When testosterone propionate enters the bloodstream, the enzyme “esterase” breaks the bond between ester and testosterone. The esters will be removed from the body leaving the testosterone free. The half-life of testosterone is just 2 to 4 hours, when propionate is bonded to it, the half-life increases to about four and a half days.
The testosterone promotes nitrogen retention in the muscle which in-turn increases the protein levels, leading to increased size and strength of the muscle. It also increases the body’s IGF-1 levels, which plays a key role in coordinating growth and metabolism.
How to take testosterone propionate inj.100 mg/ml?
Testosterone propionate is an oil-based compound and is injected into the body through intramuscular route. It is injected into the strong muscle, usually buttock muscle, every other day, not more than thrice a week. Athletes can use it twice a week. The drug should not be given to the vein. Increasing the dose and abrupt discontinuation of the drug may cause complications, and should be done only after consulting the doctor.
Warnings and precautions with the use of testosterone propionate inj.100 mg/ml
Testosterone propionate inj. should not be prescribed if the patient is allergic to testosterone. It should be avoided in patients with:
- Breast cancer, prostate cancer, heart, liver or kidney disease
- Sleep apnea, high blood levels of calcium, diabetes lung disease
- Pregnant and breast-feeding women as the drug may affect the baby
Certain precautions should be followed for effective use of the drug:
- If the patient is taking the drug at home, he or she should learn the usage instructions from the doctor.
- Do not stop the drug if you are taking it for an extended period. Do not increase the drug dosage without notifying the doctor. This is to avoid the abnormal drug-seeking behavior, which is possible with the drug.
The following tests are usually performed to monitor the progress of the condition and to check for the side effects:
- Blood testosterone levels
- Red blood cell counts
- Liver functions tests
- Blood cholesterol levels
- PSA test
Possible side effects of testosterone propionate inj.100 mg/ml
Testosterone propionate inj. has very few side effects when taken in safer dose i.e., 4ml per week or less. The severity and side effects depend on the dose, duration of circulating free testosterone, and its conversion to estrogen. Prolong use or taking the drug in higher dose may cause gynecomastia (formation of breast tissue in males), water retention, high cholesterol, and high blood pressure. Also, taking exogenous testosterone suppresses the body’s natural production of testosterone. However, once the drug intake stops, the natural production of testosterone begin.
The patient may feel pain, irritation, and redness at the injection site; however, this does not long for more than three days. The drug gets easily converted into estrogen which may cause gynacomastia, acne, and hair loss.
The side effects can be managed by taking a diet full of healthy omega fatty acids and exercising regularly.
Overdose and missed dose of testosterone propionate inj.100 mg/ml
Overdose: If the patient takes increased dose or uses it for a longer time than prescribed, especially for muscle-enhancing effects, he or she may likely show abnormal drug-seeking behavior. The overdose may also increase the risk of heart disease stroke, liver disease, ruptured tendons, or ligament.
Missed dose: It is very important to take each specified dose as directed by the doctor to get the best possible results. If you miss the dose, consult the doctor immediately to establish a new dosing schedule. Do not double the dose.
Pregnant women should not take this drug as it hampers the fetal development. The drug is passed into the breast milk, therefore, breastfeeding women should avoid taking this drug.
Patients taking the below listed medications should avoid testosterone propionate injection as drug- drug interactions such as bleeding have been reported.
- Antidiabetic drugs
- Oxyphenbutazone, propranolol
- Steroid medicines like prednisone or cortisone